Conveners
Mon 18: Protein Structure and Evolution
- Markus Schwarzländer
Photosynthesis is a fundamental process in biology as it converts solar energy into chemical energy and thus, directly or indirectly, fuels all life on earth. The chemical energy is used to fix atmospheric CO2 and produce reduced carbon compounds in the Calvin-Benson-Bassham cycle. The key enzyme for this process in all photosynthetic organisms is ribulose-1,5-bisphosphate...
Rubisco is the central CO2 fixing enzyme of the Cavin cycle and responsible for the vast majority of all CO2 fixation on our planet today. In plants, Rubisco undergoes an elaborate set of steps involving the sequential action of at least 6 different dedicated folding and assembly chaperones to assemble into its enzymatically active form. This complexity evolved from much simpler Rubisco...
Carmela GIGLIONE
Institute for Integrative Biology of the Cell (I2BC), University Paris-Saclay, CNRS, 1 avenue de la Terrasse, Gif-sur-Yvette, France
Protein modifications are emerging as key regulators of numerous essential cellular processes. Virtually all proteins undergo co- and/or post-translational modifications (CTMs, PTMs). However, a comprehensive understanding of the full range...
Rubisco is a unique catalyst involved in biological carbon dioxide fixation. It is also the most abundant protein on Earth which accumulation rises up to 50% the protein content of leaves. As a major storage protein, nitrogen recycling from Rubisco is essential during degradative processes such as plant senescence or starvation. In land plants, Rubisco functions as a large multi-subunit...
Acetylation on amino groups is a common modification seen in proteins across various organisms. This process involves N-terminal acetyltransferases (NATs) and lysine acetyltransferases (KATs) that transfer acetyl groups from acetyl-Coenzyme A (acetyl-CoA) to the N-terminal amino groups and to the side chains of lysine residues, respectively. In the case of plants, the majority of plastid...